Sarcoidosis of the Skin - SarcoidosisUK

SARCOIDOSIS AND THE SKIN

Sarcoidosis of the skin occurs in 20 to 35% of all sarcoidosis patients. Sometimes a skin condition may be the only complaint. There are several types of skin disorders that can occur with sarcoidosis including erythema nodosum, lupus pernio and cosmetic blemishes.

Erythema Nodosum

Erythema Nodosum is the most common sarcoidosis related skin condition. It often occurs in the acute form of the disease.

Symptoms:

  • sudden red, painful lumps, usually on lower legs or arms

  • often accompanied by fever, fatigue and joint pain

Treatment:

  • often improves spontaneously after 3 to 6 weeks

  • purple-blue colouring may remain visible for a few weeks

  • within 6 months 80% cases heal completely without scarring

The majority of patients with erythema nodosum have conditions other than sarcoidosis (e.g. bacteria or fungal infections). In addition, certain medications can cause it. This skin condition does not always automatically indicate sarcoidosis.

Lupus Pernio

Lupus Pernio can also occur in sarcoidosis.

Symptoms:

  • blue/red flat discoloration, or swelling

  • painful skin

  • superficial lesions

  • occurs on the face, ears, fingers or toes

Treatment:

Lupus pernio is a chronic condition; it rarely disappears spontaneously and can cause permanent damage to the skin where it occurs. Proper and timely medication for this skin condition is very important. However, it is sometimes difficult to treat.

Lesions

The skin may produce thick bumps (nodules) and smaller bumps of a few millimeters in diameter (papules). In some cases, these bulges sit so close together that they form a sort of plate, also called plaque. These lesions most commonly occur on the extremities, face, scalp, back, and buttocks. Patients with plaque lesions usually have more severe systemic involvement.

Symptoms:

  • lumps in the skin

  • colour varies from red/blue to yellow/red

  • plaques feel hard and sometimes form a ring on the skin

Techniques to Understand your Condition

The progression of skin sarcoidosis varies, usually keeping pace with the diseases activity in the lung.

In most cases, a review of the skin by a dermatologist (specialist skin doctor) is sufficient.

Sometimes it is necessary to take a biopsy of the skin. Your doctor will take a test piece of skin to be examined under a microscope.

Inspect your Skin!

Sarcoidosis can cause changes to the skin. Pay particular and regular attention to:

  • tattoos;

  • old scars;

  • white or even dark-colored spots on the skin (hypo- and hyperpigmentation).

If you notice any changes in your skin, it is wise to have these checked by your doctor.

Treatment

Skin disorders during sarcoidosis are often spontaneous and pose no threat to general health. Therefore, full recovery is seen in many cases. However sometimes the skin is so damaged, painful or disfiguring that the patient feels very uncomfortable. Skin lesions take time to recover. In these cases, the dermatologist may prescribe the following medications:

  • Ointment or cream: these contain corticosteroids which suppress the inflammation of the skin. The disadvantage of corticosteroids is that they can make the skin thin and fragile in the long term.

  • Corticosteroid tablets (e.g. prednisone): may be prescribed for severely disfiguring disorders and conditions that do not heal spontaneously. The treatment with these drugs usually takes a number of months. Prescriptions will only be given in the most serious of cases due to adverse side effects of corticosteroids.

  • Cytostatic drugs: these drugs inhibit cell division and are only prescribed if corticosteroids do not provide sufficient recovery.

  • (Hydroxy) Chloroquine: originally a medicine for malaria. Dermatologists may prescribe this drug to treat lupus pernio.